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Kelvin Cain Selected Research

Apoptosomes (Apoptosome)

11/2003Diarylurea compounds inhibit caspase activation by preventing the formation of the active 700-kilodalton apoptosome complex.
11/2003Chemical-induced apoptosis: formation of the Apaf-1 apoptosome.
2/2003Characterization of the transforming growth factor-beta 1-induced apoptotic transcriptome in FaO hepatoma cells.

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Kelvin Cain Research Topics

Disease

8Neoplasms (Cancer)
01/2022 - 11/2003
2Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
09/2010 - 07/2009
1Malignant Mesothelioma
01/2021
1Mitochondrial Diseases (Mitochondrial Disease)
01/2018
1Necrosis
08/2011
1Brain Diseases (Brain Disorder)
05/2010
1Muscular Diseases (Myopathy)
05/2010
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
07/2009
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
04/2007
1Hepatocellular Carcinoma (Hepatoma)
02/2003

Drug/Important Bio-Agent (IBA)

3Proteins (Proteins, Gene)FDA Link
01/2018 - 07/2009
3CaspasesIBA
08/2011 - 02/2003
3Apoptosomes (Apoptosome)IBA
11/2003 - 02/2003
2Cytochromes c (Cytochrome c)IBA
11/2003 - 02/2003
1Proteasome Endopeptidase Complex (Proteasome)IBA
01/2022
15'-methylthioadenosine phosphorylase (methylthioadenosine nucleosidase)IBA
01/2021
1Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)IBA
01/2021
1Superoxides (Superoxide)IBA
01/2018
1Glucose (Dextrose)FDA LinkGeneric
11/2012
1Adenosine Triphosphate (ATP)IBA
11/2012
1Phosphotransferases (Kinase)IBA
08/2011
1Caspase 8 (Caspase-8)IBA
08/2011
1Protons (Proton)IBA
09/2010
1ProteomeIBA
09/2010
1Mitochondrial DNA (mtDNA)IBA
05/2010
1LipidsIBA
07/2009
15-Lipoxygenase-Activating ProteinsIBA
07/2009
1LeukotrienesIBA
07/2009
1EnzymesIBA
07/2009
1MK-886IBA
07/2009
12,3,5- trimethyl- 6- (12- hydroxy- 5,10- dodecadiynyl)- 1,4- benzoquinoneIBA
07/2009
1Transcription Factors (Transcription Factor)IBA
04/2007
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2003
1Transforming Growth Factor beta (TGF-beta)IBA
02/2003

Therapy/Procedure

1Therapeutics
01/2019